Working with Dr. Amy

A Program Tailored to Each Unique Individual

Dr. Amy’s personalized approach to health and wellness has supported children on the spectrum for well over a decade. After exploring our Getting Started page, you may want to begin The Yasko Protocol but may feel confused on how – this is normal and we’re here to guide you. The idea is to make you the expert while guiding your child on their path to optimal health, gathering tools so that you (with the assistance of your health care professional) can make informed decisions moving forward. Below, you’ll find a simplified 3 step approach to starting The Yasko Protocol. Throughout this page, we answer some frequently asked questions and provide an in depth Yasko Protocol overview.

How to work with Dr. Amy

The following steps are the easiest and fastest way to begin working with Dr. Amy

Step 1

 

Order and
Complete a
Hair Elements Test

Step 2

 

Include All in One
in your Supplement Regimen

Step 3

 

Read Dr. Amy’s FREE Book: Feel Good Nutrigenomics

Step 1

order and complete a hair elements test

• While placing your order for a Hair Elements Test, select “with” Dr. Amy’s client file review

• By selecting “with” Dr. Amy’s client file review, you will receive Dr. Amy’s feedback on your results. Consult with your health care professional on all of Dr. Amy’s suggestions

• Implement Dr. Amy’s recommendations (supplements, lifestyle changes, and next tests to complete)

Step 2

Include All in One
in your Supplement Regimen

• While waiting for Dr. Amy’s client file review from your HE Test results, begin taking All in One

• The All in One general vitamin has very low dose supports for MTHFR and The Methylation Cycle

• This helps to ensure that MTHFR, as well as The Methylation Cycle can function to some degree

• Dr. Amy truly believes that this cycle is critical for health and wellbeing

• Consult with your health care professional on all supplement choices

Step 3

Read Dr. Amy’s FREE Book: Feel Good Nutrigenomics 

• Dr. Amy’s Feel Good Nutrigenomics book is available as a FREE online resource.  Available as a hard copy as well

• This book supplies the philosophy and basis of The Yasko Protocol in layman’s terminology

• Dr. Amy gives an overview of how she approaches complex health issues by looking at the genetics of your nutritional pathway, infectious diseases, and environmental toxins. Then, Dr. Amy discusses how all of these elements overtime can interact and create health concerns. She goes on to describe how you, with the guidance from your health care professional, can address those issues. Within this book, you will also find a general overview of what SNPs are and what The Yasko Protocol is all about before you really dive in.

Frequently Asked Questions

How do I book a consultation with Dr. Amy?

With a 5+ year waiting list for consults, Dr. Amy decided over a decade ago that she needed to change her approach in working with people. As a result, Dr. Amy began to share her resources for free as a way to help support anyone who wanted to follow her protocol. Dr. Amy’s goal is to share the information you need to take control of your own health. This paradigm shift has enabled many to gain access to Dr. Amy in a way they could not have done before.

While Dr. Amy no longer offers regular consultations, you can receive her professional suggestions through a client file review (at no additional cost) by running biochemical tests. A client file review allows Dr. Amy to comment on your results, adding suggestions for your consideration that you can discuss with your health care professional. The idea is to make you the expert on your own path to health, gathering tools so that you (with the assistance of your doctor) can make informed health decisions moving forward. The Yasko Protocol can be easily modified to address your specific needs and imbalances over time. By running regular tests, Dr. Amy is able to provide updated personalized feedback and is better equipped to customize her program to your changing needs. As always, consult with your health care professional on all decisions.

What if I want to work with a physician in my area?

Upon finding a physician, Dr. Amy can provide feedback through a client file review. When ordering a test on www.HolisticHeal.com, you can choose to receive a client file review at no additional cost. This allows Dr. Amy to comment on your results, adding suggestions for your consideration that you can discuss with your health care professional.

The Yasko Protocol can be easily adjusted based on your ongoing test results in order to address your specific needs and imbalances over time. By testing regularly, Dr. Amy is able to provide updated personalized feedback and is better equipped to better help you customize your own individual health and wellness regimen.

Have Questions?

Browse the resources below, or contact us

Friendly Customer Service

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Toll free at 1-800-768-8744
or 1-207-824-8501 from
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A Detailed Overview of
The Yasko Protocol:

Read Dr. Amy’s Feel Good Nutrigenomics: Your Roadmap to Health Book

Online Copy: CLICK HERE
Hard Copy: CLICK HERE

Within this book, Dr. Amy gives an overview of how she approaches complex health issues by looking at the genetics of your nutritional pathway, infectious diseases, and environmental toxins. Then, Dr. Amy discusses how all of these elements overtime can interact and create health concerns. She goes on to describe how you, with the guidance from your health care professional, can address those issues. Within this book, you will also find a general overview of what SNPs* are and what The Yasko Protocol is all about before you really dive in. Dr. Amy considers this book as a prerequisite to reading Feel Good About your SNPs as it includes more basic concepts to help you understand the complexity of SNP interactions.

*What Exactly are SNPs?

 

SNPs (Single Nucleotide Polymorphisms) pronounced “snips”

The first step that emerged from the Human Genome Project identified genes associated with a particular health condition. The next step would be to use this information and look for the presence of genes that can cause health issues in an individual person. Rather than looking at complete gene profiles, it is also possible to look at particular changes in the “spelling” of your DNA in only specific areas of interest. In this way, you can more quickly get a sense of known genetic weaknesses. Companies that offer this service enable you to look at genes of interest that may affect your susceptibility to heart disease, inflammation, detoxification or simply your ability to absorb nutrients. These tests are available using saliva samples, cheek swabs, as well as blood samples.

In order to find relationships between genetic changes and the susceptibility to health conditions, this testing is done utilizing single nucleotide polymorphisms, otherwise known as SNPs (pronounced “snips”). This process systematically compares genomes of those individuals with health conditions to the corresponding DNA of the population. To identify a SNP is a very arduous and time consuming process as there may be 400 or more genes in a shared region, making it difficult to identify changes and trends. However, once it has been identified, making practical use of this information is quick and straightforward.

*More details about SNPs: Dr. Amy’s book Feel Good About Your SNPs + her FREE online presentation

Order our DNA Nutrigenomic Test OR Convert your Test Information

You can ORDER our DNA Nutrigenomic Test or CONVERT your Test Information if you already have SNP data within www.KnowYourGenetics.com (if you are viewing this packet, you have recently converted your information).

The reason to take your data and run it through this program is that not every company defines a plus (+) or minus (–) in the same way. What is considered “normal” (or in genetics terms, “wild type”) may differ between companies. For this reason, the program on www.KnowYourGenetics.com asks you to input the actual letter of the DNA base that was found on the test you ran. The program will then let you know if your result is something Dr. Amy personally considers as plus (+) or minus (–). At this time, if you feel you have not entered your information properly, please consider re-entering your results or calling our customer support team for assistance.

This is a test that you will need to run only once in your lifetime. Your DNA will not change so, once you have Nutrigenomic Test results, those will not change over your entire lifetime. Unlike the follow up Biochemical Testing you may consider running to routinely check that your supplementation plan is making an appropriate change to better your health, a Nutrigenomic Test focusing on The Methylation Cycle* is something you will run only one time. You will work with your doctor to determine supplementation based on these SNPs for the rest of your life. For this reason, Dr. Amy feels that everyone should run a DNA SNP test if possible to have the data you need to optimize your supplement choices overtime with your own health care professional.

For any test questions, please contact our customer support.

With respect to SNP testing, there is one critical point that Dr. Amy feels is extremely important that everyone understands: There are approximately 25,000 genes in the human genome however, Dr. Amy personally believes in only looking at SNPs that are in well-defined pathways where it is clear how to add nutritional support to bypass imbalances. Having a laundry list of SNPs without a way to use nutritional support is not consistent with the way she approaches supporting your journey to better health. As such, please note that whether you have a test that gives you 1000 or 5000 SNPs, this is still only a fraction of the total number of genes in your body. For further information on this subject, please view the note from Dr. Amy at the end of this section.

How to Read your Nutrigenomic Test results:

There are two copies of each gene that we are looking at in the profile, one copy comes from each parent.

  • Homozygous: When both copies have a particular SNP or mutation (in other words when both copies are identical) with either + + or – –
  • Heterozygous: When one copy that is + for the change and the other is – for the change

The + and – designations themselves refer to whether or not the gene has a change from what is considered “normal”. If there is a change from what is considered “normal” then it is termed as a plus (+). No change is designated by a minus (-) sign. The definition of what is “normal” can vary from lab to lab and it will depend in part on what the lab uses as a reference database. This is why you are also given the call letter for each SNP. The call letter tells you what base was seen by the lab at a precise location on the gene.

For example, when looking at the MTHFR gene, the particular SNP we are interested in is the C677T. The lab is looking at position 677 in the DNA for a change from a C to a T. If there is a change, then the call letter will show a T and the designation will be a plus (+). If there is no change, then the call letter will be C and the designation will be a minus (-). If a different lab considers the change to a T as “normal”, then they might show a T in position 677 as a minus (-), as their reference database may feel that it is normal to have a T in that position. This is why the call letter is so important. In cases where there is a discrepancy from one lab to another, the actual call letter will let you know what base was seen at a precise location. This enables you to be certain that tests run from different labs gave the same actual experimental result even if their reference standard for a “normal” change was different.

Assume the following scenario as an example: Dr. Amy is 5 feet 3 inches tall, her height will be equivalent to the call letter in this analogy as it is a precise measurement. If she compares her height to that of her children, Dr. Amy is taller than her youngest, the same height as her eldest, and shorter than her middle child. Using Dr. Amy’s daughters as a reference base, Dr. Amy would consider her own height as average. However, if she compares her height to that of the rest of the population of her hometown, Dr. Amy is actually quite short since many of the individuals in her town are very tall. Using the + + and – – designations, she might be + – if the reference database was to her children, or + + if the reference database was to her hometown. In either event, Dr. Amy’s height by precise measurement is 5 feet 3 inches and that will not change. Knowing the lab value allows Dr. Amy to compare her height to other databases in the future.

Guide to Minus (-) and Plus (+) Results:

  • Minus (-) represents no mutation, in other words considered “normal”
  • Plus (+) represents a mutation, in other worse not the standard / not “normal”
  • Minus Minus (- -) indicates there is no mutation: Homozygous
  • Plus Minus (+ -) indicates there is one mutation: Heterozygous
  • Plus Plus (+ +) indicates there is a double mutation: Homozygous

Guide to Color-Coded Results:

  • A red background indicates a greater level of support is needed
  • A yellow background indicates that support is needed, but to a lesser degree than red
  • A green background indicates that there is little to no support needed

Please note: The results column is color coded to correspond with the level of the support needed, so you may see some + – in red. For questions that you maybe have about your results, please utilize the discussion group at www.Ch3Nutrigenomics.com and, as always, consult with your health care professional.

A Note from Dr. Amy about DNA Nutrigenomic Testing:

Focusing on 30 SNPs
While there are thousands of genes and SNPs that I could look at, for my health program I have chosen to focus on the 30 SNPs that are part of a nutritional pathway in the body. It is not a panel that looks at specific genes that are involved in cancer or various disease states. Rather, it is a panel that looks at a natural nutritional pathway that is central to overall health and wellbeing. While many DNA panels work on the ‘more is better’ philosophy, I do not. Even if you ran a panel that looks at more than the 30 key SNPs I review, it is still only a small fraction of the total genes and SNPs in your body as you have about 25,000 genes in your body, some of which may have SNPs or mutations that impact their function.

Sharing Personal Information
I do have some ethical concerns with the ‘more is better’ approach of looking at a multitude of SNPs in your DNA. It has been stated that some of these companies are focused primarily on future research projects by sharing your data with other laboratories. I am not sharing or selling your data, the only purpose of the SNP test from the panel I designed is for me to place it in your personal file so I can refer to it when I look at Biochemical Test results that you run. The laboratory that runs my SNP panel does not store any patient information and the blood or cheek swab samples are de-identified and discarded after 60 days: “Communication that occurs between our laboratories points to the Lab ID number – not patient name”, in addition, “Genetic tests are handled in a confidential manner, like all other personal health information. Test results are released to the ordering health care provider, and to those parties entitled to them by state and local laws, or to a person whom you have specifically authorized by signing a written release” (https://www.doctorsdata.com/online-privacy).

Conversely, some of the ‘more is better’ SNP tests come from companies that are able to offer a discounted price as their ultimate aim is to gather genetic information. It appears that they absorb some of the cost of the test itself in order to have a larger number of individuals ordering the tests so that they can gather more information, which is not kept confidential. A board member of one of these companies has publicly stated: “The long game here is not to make money selling kits, although the kits are essential to get the base level data…Once you have the data, [the company] does actually become the Google of personalized health care[…] The company has lowered the price of the kit again and again, most recently from $299 to a mere $99, practically making it a stocking-stuffer. All the better to induce volunteers to give the data it so desperately wants” (Zhang, July 2018. The Atlantic). It may not matter to you that your data will be shared, just be sure you are making an informed choice.

Please note that if you cannot afford a more targeted and confidential SNP panel and have chosen a lower cost option, that is absolutely okay. I would rather have some SNP data, even if some of the key SNPs are missing, than no data at all. That is why I have set up my protocol to include data from any panel. My goal is to have the most information in your file so that I can do the best possible job of making suggestions for you and your personal doctor to consider implementing to achieve optimal health.

Problem without a Solution
My final concern about ‘more is better’ SNP panels is that they often tell you there is an imbalance, yet they have no knowledge of nutritional paths around the issue identified. They also do not look to assure you that just because a SNP has been found, that it is not necessarily a cause for panic*. I only believe in looking at DNA profiles and SNPs that yield information that can be addressed with nutrients. I do not believe in testing just for the sake of testing, which is why I am not a ‘more is better’ advocate in terms of the number of SNPs data on a given test. I believe that DNA testing without any knowledge of how to address the issues that are uncovered is unethical. I believe in targeted testing in a defined nutritional pathway so you have options for natural supports to bypass imbalances that are found and make a positive difference.

The beauty of looking at targeted SNPs in The Methylation Cycle is that it is a nutritional pathway, so you can consider natural products to help support imbalances or SNPs that are found in this pathway. Nutrigenomic Test results that look at SNPs in your DNA should help to put your mind at ease by giving you suggestions that you can act on. Nutrigenomics is a form of Genetic Testing that supplies information that can translate into positive constructive action. I see the ultimate goal of Nutrigenomic Testing to serve as a guide toward proper supplementation to bypass genetic weaknesses identified by SNP results. I believe in running follow up Biochemical Tests to be sure that the nutritional supplements added have the desired positive impact. My ultimate goal is to use Nutrigenomic Testing as a guide to proper supplementation to bypass genetic weaknesses, under the purview of your own doctor.

*More details about SNPs: Dr. Amy’s book Feel Good About Your SNPs + her FREE online presentation

*For a basic understanding of The Methylation Cycle, please view Dr. Amy’s book Feel Good Nutrigenomics: Your Roadmap to Health

Online Copy: CLICK HERE
Hard Copy: CLICK HERE

Start Step One Support

Start “Step One Support” within Your Roadmap to Health

Step One Support: GF/CF Diet, Limit Excitotoxins, Balance Gaba/Glutamate, Review the Methylation Support Sheet* for Basic Methylation Support, Add in Supports for Organ Systems as described in the Companion Guide on pages 15 to 26.

*Methylation Support Sheet: This support sheet includes links that lead you directly to the products ecommerce site and is available within Your Roadmap to Health.

*Your Health Companion: Dr. Amy’s Health Companion is a FREE user friendly, personalized client portal to help support your journey to better health and wellness. Within this secure system, you can access your Client History Form, Supplement List, Test Results, and more! This wonderful system will help to organize your important information for years to come, saving all files within our client portal for you to access and reference easily.
To Learn More: CLICK HERE

While you may already be on the GF/CF diet (which Dr. Amy recommends), there is an additional step to the diet that needs to be made in order for the inflammatory process to abate and the recovery process to begin. This additional dietary step/intervention is to remove/reduce excitotoxins from the diet and from supplements as well.

Excitotoxins are: Glutamate, Glutamic Acid, MSG, Glutamine (which converts to Glutamate), Aspartate, Aspartame, NutraSweet, and Cysteine. Foods that are especially high in Glutamate are: Soy, Peas, Mushrooms, Tomatoes, Beets.

A diet high in fermented foods and/or high protein may also contribute to this issue. It is important to be conscious of the total load of Glutamate and to think of your ability to tolerate more Glutamate as if your cup is already full to the brim and about ready to overflow.

Dr. Amy feels that it is important to balance Glutamate and Gaba in part by pulling down Glutamate levels that are too high. Products you can consider for help with this process include: BeCalm Spray, Ku Shen Tea, Gaba Balance, Nerve Calm Nucleotide Blend, Resveratrol Spray, Pycnogenol, and Grape Seed Extract.

Please note that it is not necessary to use all of these. Which products you choose will depend on your health care professional’s opinion considering how much of an issue Glutamate is for your body and which supplements your body will respond well to.

Also, Glutamate works with Calcium to cause excitotoxicity, so keeping Calcium in balance with products such as Zinc, low doses of Lithium, and low doses of Magnesium can be helpful.

What is not included in The Yasko Protocol: Glutamate/Glutamine. The following are not included in The Yasko Protocol in high doses: Calcium, TMG/Betaine, Folate, Folinic, 5 Methylfolate, or B6. Those who follow the DAN protocol, a diet high in fermented foods, a diet high in protein, or those who have been using high doses of 5MTHF, chelating agents and/or higher doses of Methyl B12, may find that they especially need to balance Lithium, get Gaba/Glutamate supports and extra organ supports on board.

Dr. Amy’s All In One supplement is a custom general vitamin, taking into account the imbalances she has seen on thousands of tests for over a decade. Dr. Amy believes All in One can help lay the nutritional groundwork for essentially everyone on the program, including those who are sensitive to Sulfur and/or Methyl Donors, along with those who are MTHFR+, CBS+, etc. All in One contains very low dose Lithium, the preferred forms of several important key minerals, and very low dose supports for The Methylation Cycle. This helps to ensure that The Methylation Cycle can function to some degree at a very low level regardless of your SNP profile.

Suggested use is to start with a single capsule and gradually work up to the suggested 3-4 capsules per day, as tolerated. Although opening the capsule may expose the ingredients to oxygen, it should be fine for those who are younger, sensitive or new to the program who need to start with just a sprinkle.

For more information on All in One ingredients and rationale, please reference the Discussion Group (to view this link, please signup/log into the Discussion Group) or contact our customer support.

We all need organ supports including Adrenal, Kidney, Pancreatic, and Liver. Those with certain genetics, certain Biochemical Test results and/or a history of Chelation may need extra supports. Organ supports to consider include MTHFR A1298C+ Liver Support, VDR / FOK Pancreatic Support, Ultimate B Complex, Special Digestive Enzymes, Intact Multigland, and Kidney Beef.

Next, you can work with your health care professional to get some Basic Methylation support in place. Start with the Basic Methylation Support Sheet*, looking at the use of Phosphatidyl Serine Complex, along with SAMe (if it is tolerated), VitaOrgan, and DHA Neuromins.

*Basic Methylation Support Sheet: This support sheet includes links that lead you directly to the products ecommerce site and is available within Your Roadmap to Health.

Low doses of Lithium supports are also important for everyone to consider. Both All in One and the BeCalm Spray are excellent sources for this purpose. The doses are well tolerated even for those just starting The Yasko Protocol. This low level of Lithium may not be sufficient to support those who have very low Lithium levels on a Hair Elements Test (HE). Once you have received your test results to check that your Lithium levels are in balance by running a Urine Toxic & Essential Elements Test (UTEE) and Hair Elements Test (HE), work with your doctor on additional low dose Lithium supports as needed. Options to discuss with your health care professional for additional Lithium support include Lithium Orotate capsules and Lithium Drops. If needed in unique cases, prescription Lithium can be obtained from your doctor. Where Lithium plays a role in B12 transport, if you start to add too much B12 before Lithium is in balance, you run the risk of further depleting Lithium levels.

For any of these supports mentioned, the “low and slow” method is suggested. Dr Amy considers a “sprinkle” a bonafide dose. Just by stopping a supplement or changing your diet you may see detox, consider running ongoing Biochemical Testing to recognize these changes and implement appropriate supplementation to control it. As always, work and consult with your own health care professional. Remember, this is a marathon not a sprint!

A Note from Dr. Amy about Supplementation:

Choices I make in terms of supplements are based on their impact on test results and this is a unique approach that is not taken by others who are solely looking to sell supplements. I see supplements as a much needed tool for health, not as a commodity. I see the whole person, not just a test file. I see your health history and future health goals. I truly feel passionate about supporting your health goals for both yourself and your loved ones. When I talk about supplements please understand I am not making claims, nor stating that any supplement or herb will cure a given health condition. My concern about supplement source is related to the fact that I find it a true privilege to be a part of so many lives and to be given the opportunity to help others. I receive emails and test results from individuals daily who are following The Yasko Protocol where their lives are being changed in a really amazing way. Those who follow my protocol as designed and use the correct products really do see wonderful results. When I see such progress, it is due in part to supplements being added as indicated by the suggestions I include based on test results, and when tests were done on a regular basis. This is what I want to see for each and every one of you, this is why I do what I do each day. I hope that you understand my focus on supplement source and quality comes from a place of caring. I always want to see positive progress on your follow up tests, I want to hear stories of success from each and every one of you, and I want all of you to be able to achieve the health you are looking for. Please see my Feel Good Supplements Guidebook (everyone should receive one free copy automatically when they order from www.HolisticHeal.com) to learn more about the importance of this topic.

Hair Elements Test and Urine Essential Element Test

Order a Hair Elements Test (HE) and if financially feasible, also order a Urine Essential Element Test (UEE) to ensure your Lithium levels are in balance. Please recall that Lithium is important for B12 transport.

For any test questions, please contact our customer support.

Lithium

Lithium not only plays a role in mood, Glutamate control and limiting aggression, but also has been shown to be involved in B12 transport. Many adults (as well as individuals who are MTR A2756G+) tend to have lower levels of Lithium as judged by Hair Elements Test (HE). Supporting with higher levels of B12 before having ascertained that Lithium is in balance may lead to further depletion of Lithium levels. For this reason, Dr. Amy highly suggests running a Hair Elements Test (HE) and/or a Blood Lithium Test (that can be run through your health care professional), along with a Urine Essential Element Test (UEE) to assess the Lithium levels in your system. If Lithium levels are low in hair, blood or urine, please consider additional Lithium supplementation with your doctor before moving onto B12 support. Similarly, if very high levels of Lithium excretion are showing up on your UEE Test, one should consider additional Lithium supports with their health care professional prior to transitioning to B12 support. Sources of Lithium support can include BeCalm Spray, low doses of Lithium Orotate, and All in One. The level of support needed should be determined by a combination of running Biochemical Tests as well as a consultation with your personal health care professional.

Work on increasing B12 while continuing to track levels of Lithium to be sure it stays in balance while increasing B12. Running a HE Test consistently can help monitor Lithium levels while increasing B12 supports.

Determine Your Ideal Form of B12

Once your Lithium levels are in balance and Basic Methylation is in place, increasing B12 support will be the next step. In conjunction with paying attention to your B12 levels, you can begin to customize your supplement plan based on your test results. Your Nutrigenomic Test results can guide you through individualizing your supplementation choices. While we all need B12, each person is unique in which form of B12 will best suit their body. If you have chosen to add All in One or/and Ultimate B Complex to your supplements, you are already getting some low doses of B12 support. The forms of B12 in both of those vitamins are designed to be tolerated by all, but now it is time to add in some specific B12 supports based on your Nutrigenomic Test results. The chart below will help you to determine which form of B12 might be best tolerated by your system.

Please note that while this chart can help guide you to choose the type of B12 support based on Nutrigenomic Test results, it is also important to pay attention to what your body is telling you. It is important to know that individuals who tend to have a more difficult time with any supplements that can trigger detox may also have issues with Methyl B12. As such, if you are having trouble tolerating Methyl B12, then listen to your body’s reaction and instead discuss with your doctor about switching to Hydroxy B12 with some Adenosyl B12 as an alternative approach to B12. For a more detailed description of the different types of B12, along with references for their uses, please view the content after the chart below.

COMT V158M VDR Taq B12 Types that Should be Tolerated
– – + + (TT) All 3 types of B12
– – + – (Tt) All 3 types with less Methyl B12
– – – – (tt) Hydroxy B12 and Adenosyl B12
+ – + + All 3 types with less Methyl B12
+ – + – Hydroxy B12 and Adenosyl B12
+ – – – Hydroxy B12 and Adenosyl B12
+ + + + Hydroxy B12 and Adenosyl B12
+ + + – Hydroxy B12 and Adenosyl B12
+ + – – Mostly Hydroxy B12

Why it is so important to have a form of B12 that you can tolerate:

  • Vitamin B12 is a water soluble vitamin, this means that it does not stay in the body for a long period of time and that more frequent support with B12 may be needed to maintain healthy B12 levels in the body.
  • Vitamin B12 is important for energy, balance related sports, endurance sports, healthy red blood cells, memory, among other roles in the body.
  • Vitamin B12 can be depleted by drinking alcoholic beverages, a poor diet, certain medications, and simply just as we age.
  • Lack of B12 has been associated with fatigue, alcoholic liver disease, anemia, cancer, ulcers, dementia, neural tube defects, depression, and memory loss.
  • Higher levels of B12 correlate with improved balance, energy, and endurance in athletics.

Different types of B12 work best for different people:

Vitamin B12 (also called Cobalamin) can include Hydroxy B12, Methyl B12, Cyano B12, and Adenosyl B12. Many vitamins (including B12) are not active in the form in which they are normally found in food. Instead, the body needs to convert the B12 into a form that it can use directly. B12 is needed for the proper functioning of a number of different enzymes in the body however, not all types of B12 are equal and not all types of B12 can be easily changed to what is needed for critical reactions in the body. Hydroxy, Methyl, and Adenosyl are all forms of B12 that are used directly by reactions in the body. Cyano must be converted for use in the body and as the name suggests, Cyanocobalamin contains a Cyanide Molecule.

Methyl B12 can be used in the body, though it cannot be tolerated by everyone. Those who get jittery from caffeine may not react as well to Methyl B12. Many adults do not do as well with Methyl B12 in spite of their nutrigenomics and so, it is suggested to choose an alternate form.

Adenosyl B12 is a special form of B12 that is important in the energy cycle in the cells of your body. It is important to have Adenosyl B12 however, please know this form of B12 is not as versatile as other forms of B12. As such, it can be used in lower doses.

Hydroxy B12 (or Hydroxycobalamin) is a unique form of vitamin B12 which is more easily converted to the form that is used for reactions in the body. This might cause you wonder why all products would not simply use high dose Hydroxy B12 in their formulations. Hydroxy B12 is more difficult to work with, harder to keep in an active form, and more expensive than some other forms of B12 (such as Cyano B12). For these reasons, many other products do not contain Hydroxy B12 and instead use Cyano B12.

Cyano B12 contains a Cyanide Molecule. As such, when you take Cyano B12, your body must first turn it into Hydroxy B12 in order to use it. Your body then must find a way to get rid of the toxic Cyanide Molecule. It is important to note that Cyanide is a poison, even if the rest of the B12 molecule is good for you and the body actually uses up Hydroxy B12 in order to detoxify Cyanide. So, not only is Cyano B12 not the form your body ultimately needs, but taking higher doses of Cyano B12 may actually deplete your body’s natural levels of Hydroxy B12. This may cause you to wonder why anyone would use Cyano B12 if it can be toxic. In low doses, Cyano B12 may be helpful for the eyes, but for the most part Cyano B12 is used because it is much less expensive and a form of B12 that is easier to keep stable when stored.

For a complete list of B12 support: CLICK HERE

Start Full Methylation Support

Start “Full Methylation Support” within Your Roadmap to Health

Full Methylation Support: Methyl Folate 5-MTHF Drops, Folinic+ Capsules, Additional B12 Supports (type of B12 depends on SNPs), and also Review the Methylation Support Sheet*

Please Note: When starting the next step of Full Methylation Support, this does not mean that you should stop any of the steps within Step One Support (view the above section titled “Start Step One Support within Your Roadmap to Health” for more details). Specifically, use both Basic Methylation Supports and Full Methylation Supports

*Methylation Support Sheet: This support sheet includes links that lead you directly to the products ecommerce site and is available within Your Roadmap to Health.

*Your Health Companion: Dr. Amy’s Health Companion is a FREE user friendly, personalized client portal to help support your journey to better health and wellness. Within this secure system, you can access your Client History Form, Supplement List, Test Results, and more! This wonderful system will help to organize your important information for years to come, saving all files within our client portal for you to access and reference easily.

To Learn More: CLICK HERE

Biochemical Testing

Biochemical Testing measures the amount or activity of a particular enzyme or protein from a sample of urine, stool, or hair. The Biochemical Tests help to assess progress with methylation as well as nutrient absorption and neurotransmitter levels. As depicted on Your Roadmap to Health, Biochemical Testing is an ongoing tool that you can use to assess your current progress and to know when and how to proceed. Please refer to the Companion Guide on pages 27 to 53.

Dr. Amy uses Biochemical Testing in conjunction with DNA SNP Data to customize her supplement suggestions specifically for your unique needs. Follow up Biochemical Testing can be done routinely to check that your supplementation plan is making an appropriate change to better your health. Unlike Genetic Tests, Biochemical Test results will change over time. The goal is to use the knowledge of your genetics to make informed decisions on how to supplement and bypass weaknesses in your system and then to use regular Biochemical Testing to monitor the progress of your supplementation to bypass mutations.

When Dr. Amy completes her client file review on a test you’ve run, she includes a sheet that offers suggestions for the next Biochemical Test to run based on what your current test results are. These test suggestions from Dr. Amy are there to help guide you and your health care professional through The Yasko Protocol. Dr. Amy also makes suggestions within her book Feel Good About Your SNPs about specific Biochemical Tests. Within her book, Dr. Amy discusses which Biochemical Tests will be of most value to you depending on your specific SNPs.

Also, for further information on Biochemical Testing, please view Dr. Amy’s free online book: Feel Good Biochemistry. This resource goes through each biochemical test and explains how Dr Amy views the results of those tests and details suggestions she would make on a test. This is an amazing resource for you and your doctor to be able to run tests and get her viewpoint on the results.

It is suggested to run a UTM and UEE, a UAA, and a HE when starting the program, during Step One Support and/or adding Basic Methylation Supports. Please refer to the Companion Guide on pages 55 to 58 for a basic understanding and explanation of these test results, along with viewing Feel Good Biochemistry.

  • HE can be run while waiting for genetics results and will help to assess detox, Lithium and other essential element levels.
  • UTM and UEE can be run while waiting for genetic results and will help to assess minerals levels, determine detox and creatinine.
  • UAA can be run while waiting for genetics results and will help to assess Ammonia, Taurine, Glutamate, Gaba and other amino acid levels.

Please note that Dr. Amy likes the OAT Test and the NC Test to be run together for those who have concerns about stress, behavioral patterns, mood, and issues with attention.

Also, Dr. Amy occasionally will graph your hair, urine, and fecal toxic tests as an additional way to monitor your progress.

For any test questions, please contact our customer support.

Understanding Your Genetic Results: Priority of Mutations

Once you have reviewed your Nutrigenomic Test results and have Step One/Basic Methylation Supports in place, please refer to:

Feel Good About Your SNPs book + the Corresponding FREE Online Presentation

The Companion Guide on pages 60 to 63